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StemRD GDC-0449, SMO antagonist 拮抗劑
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產(chǎn)品型號(hào):
GDC-25
產(chǎn)品報(bào)價(jià):
產(chǎn)品特點(diǎn):
StemRD GDC-0449, SMO antagonist 拮抗劑
規(guī)格型號(hào):25mg/支
  GDC-25StemRD GDC-0449, SMO antagonist 拮抗劑的詳細(xì)資料:

StemRD GDC-0449, SMO antagonist 拮抗劑 產(chǎn)品英文簡(jiǎn)述:

GDC-0449 (Vismodegib): A potent antagonist of SMO (smoothened). This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molecule has been developed by Genentech for clinical application against hedgehog-dependent cancers.
 
Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives IC50 of 5-20 nM.

重慶市華雅干細(xì)胞技術(shù)有限公司

產(chǎn)品相關(guān)關(guān)鍵字: StemRD GDC-0449 GDC-0449 SMO antagonist 拮抗劑
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